WB 1:500-1:2000; IHC 1:50-1:200
A phospho specific peptide corresponding to residues surrounding S253 of human FOXO3
Human, Mouse, Rat
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
FOXO3; AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; forkhead box O3