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Rabbit Anti-Phospho-GIT2 (Tyr592) Recombinant Antibody (D6L1J) (CBMAB-CP0830-LY)

The product is antibody recognizes Phospho-GIT2 (Tyr592). The antibody D6L1J immunoassay techniques such as: WB.
Host Animal
Rabbit
Application
WB
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr592 of human GIT2 protein.
Antibody Isotype
IgG
Cross Reactivity
Human
Clone
D6L1J
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
Alternative Name
GIT ArfGAP 2; G Protein-Coupled Receptor Kinase Interacting ArfGAP 2; Cool-Interacting Tyrosine-Phosphorylated Protein 2; G Protein-Coupled Receptor Kinase-Interactor 2; GRK-Interacting Protein 2; Paxillin Kinase Linker; ARF GAP GIT2; CAT-2;
Entrez Gene ID
UniProt ID
Cat CBMAB-CP0830-LY
Conjugates
Size
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