Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser368 of human connexin 43 protein.
Human, Mouse, Rat
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]
Gap Junction Protein Alpha 1; Gap Junction Protein; Alpha 1; 43kDa; Gap Junction 43 KDa Heart Protein; Connexin-43; CX43; GJAL; Gap Junction Protein; Alpha 1; 43kDa (Connexin 43); Oculodentodigital Dysplasia (Syndactyly Type III); Gap Junction Protein; Alpha-Like; Gap Junction Alpha-1 Protein;