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Rabbit Anti-SLC31A1 Recombinant Antibody (CBXS-1590) (CBMAB-S4439-CQ)

This product is a rabbit antibody that recognizes SLC31A1. The antibody CBXS-1590 can be used for immunoassay techniques such as: WB, FC.
See all SLC31A1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1590
Antibody Isotype
IgG
Application
WB, FC

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLC31A1
Introduction
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper.
Entrez Gene ID
Human1317
Mouse20529
Rat171135
UniProt ID
HumanO15431
MouseQ8K211
RatQ9JK41
Alternative Names
Solute Carrier Family 31 Member 1; Solute Carrier Family 31 (Copper Transporter), Member 1; Copper Transporter 1; COPT1; CTR1; Solute Carrier Family 31 (Copper Transporters), Member 1;
Function
High-affinity, saturable copper transporter involved in dietary copper uptake.
Biological Process
Biological Process cellular copper ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process copper ion importIEA:Ensembl
Biological Process copper ion transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process establishment of localization in cellIEA:Ensembl
Cellular Location
Cell membrane
Localizes to the apical membrane in intestinal epithelial cells.
Topology
Extracellular: 1-61
Helical: 62-82
Cytoplasmic: 83-132
Helical: 133-153
Extracellular: 154-156
Helical: 157-177
Cytoplasmic: 178-190
PTM
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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