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Mouse Anti-SLC31A1 Antibody (11BA30) (CBMAB-1584CQ)

This product is a mouse antibody that recognizes SLC31A1. The antibody 11BA30 can be used for immunoassay techniques such as: ELISA.
See all SLC31A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
11BA30
Antibody Isotype
IgG2b
Application
ELISA

Basic Information

Immunogen
Synthetic Peptide (RKSQVSIRYNSMPVPGPNGTIL)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLC31A1
Introduction
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. Diseases associated with SLC31A1 include Wilson Disease and Ethylmalonic Encephalopathy. Among its related pathways are Metal ion SLC transporters and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
Entrez Gene ID
1317
UniProt ID
O15431
Alternative Names
Solute Carrier Family 31 (Copper Transporter); Member 1; COPT1; CTR1; Copper Transporter 1; Solute Carrier Family 31 Member 1; Copper Transport 1 Homolog (S. Cerevisiae); Copper Transport 1 Homolog; High Affinity Copper Uptake Protein 1; Solute Carrier Family 31 (Copper Transporters); Member 1; hCTR1
Function
High-affinity, saturable copper transporter involved in dietary copper uptake.
Biological Process
Biological Process cellular copper ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process copper ion importIEA:Ensembl
Biological Process copper ion transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process establishment of localization in cellIEA:Ensembl
Cellular Location
Cell membrane
Localizes to the apical membrane in intestinal epithelial cells.
Topology
Extracellular: 1-61
Helical: 62-82
Cytoplasmic: 83-132
Helical: 133-153
Extracellular: 154-156
Helical: 157-177
Cytoplasmic: 178-190
PTM
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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