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Mouse Anti-SLC44A1 Recombinant Antibody (CBXS-2718) (CBMAB-S5469-CQ)

This product is a mouse antibody that recognizes SLC44A1. The antibody CBXS-2718 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC44A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2718
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa74-184 from SLC44A1 (NP_536856) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 44, member 1
Entrez Gene ID
23446
UniProt ID
Q8WWI5
Alternative Names
Solute Carrier Family 44 Member 1; Solute Carrier Family 44 (Choline Transporter), Member 1; CDW92 Antigen; CDW92; CD92; CTL1; Choline Transporter-Like Protein 1; CD92 Antigen; CHTL1;
Function
Choline transporter. Involved in membrane synthesis and myelin production.
Biological Process
Biological Process choline catabolic processTAS:Reactome
Biological Process choline transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process phosphatidylcholine biosynthetic processTAS:Reactome
Biological Process transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process transport across blood-brain barrier2 PublicationsNAS:ARUK-UCL
Cellular Location
Cell membrane
Mitochondrion outer membrane
Involvement in disease
Neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline (CONATOC):
An autosomal recessive neurodegenerative disease characterized by progressive ataxia, tremor, cognitive decline, dysphagia, optic atrophy, dysarthria, as well as urinary and bowel incontinence. Brain MRI demonstrates cerebellar atrophy and leukoencephalopathy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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