Recombinant 25.7 kDa protein fragment of SNIP1
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. The protein is also involved in the microRNA (miRNA) biogenesis.