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Mouse Anti-TAX1BP3 Recombinant Antibody (4A10) (CBMAB-A8886-LY)

The product is antibody recognizes TAX1BP3. The antibody 4A10 immunoassay techniques such as: WB, ELISA.
See all TAX1BP3 antibodies
Published Data
Fig. 1 Total proteins were extracted from the same cells, separated by SDS–PAGE, electroblotted and immunoprobed with anti-GEF16 and anti-Tip-1. Anti-GAPDH was used as a loading control.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
4A10
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TAX1BP3 (AAH23980, 1 a.a. ~ 124 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Tax1 (human T-cell leukemia virus type I) binding protein 3
Entrez Gene ID
30851
UniProt ID
O14907
Alternative Names
TIP-1
Function
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
Biological Process
Biological Process activation of GTPase activityIDA:BHF-UCL1 Publication
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of protein localization to cell surfaceIDA:UniProtKB1 Publication
Biological Process negative regulation of Wnt signaling pathwayISS:UniProtKB
Biological Process Rho protein signal transductionIDA:UniProtKB1 Publication
Biological Process Wnt signaling pathwayIEA:UniProtKB-KW
Cellular Location
Cytoplasm
Nucleus
Cell membrane
Recruited to the cell membrane by interaction with membrane proteins.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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