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Human ATR Peptide (LFPFEAEAY) (PEP-131224CQ)

This product is synthetic peptide that is derived from Human ATR (AA 302-310). This peptide sequence corresponds to amino acid residues: LFPFEAEAY.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Alternative Name
ATR Serine/Threonine Kinase; Ataxia Telangiectasia And Rad3-Related Protein; EC 2.7.11.1; FRP1; MEC1, Mitosis Entry Checkpoint 1, Homolog (S. Cerevisiae); MEC1, Mitosis Entry Checkpoint 1, Homolog; Ataxia Telangiectasia And Rad3 Related; Serine/Threonine-Protein Kinase ATR;
Entrez Gene ID
UniProt ID