Human BAG3 Peptide (VYPQPGMQRF) (PEP-100501CQ)

This product is synthetic peptide that is derived from Human BAG3 (AA 113-122). This peptide sequence corresponds to amino acid residues: VYPQPGMQRF.
Lyophilized powder
Store at -20°C
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alternative Name
BCL2 Associated Athanogene 3; Bcl-2-Binding Protein Bis; Docking Protein CAIR-1; BAG-3; BIS; BAG Family Molecular Chaperone Regulator 3;
Entrez Gene ID
UniProt ID