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Human CFTR Peptide (VSLLSNNLNKFDEGL) (PEP-113103CQ)

This product is synthetic peptide that is derived from Human CFTR (AA 181-195). This peptide sequence corresponds to amino acid residues: VSLLSNNLNKFDEGL.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome.
Alternative Name
Cystic Fibrosis Transmembrane Conductance Regulator; Channel Conductance-Controlling ATPase; CAMP-Dependent Chloride Channel; EC 3.6.3.49; ABCC7; Cystic Fibrosis Transmembrane Conductance Regulator, ATP-Binding Cassette (Sub-Family C, Member 7); Cystic Fi
Entrez Gene ID
UniProt ID
Cat PEP-113103CQ
Conjugates
Size
Price $
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