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Human CHEK1 Peptide (ITIPDIKKDRW) (PEP-011513CQ)

This product is synthetic peptide that is derived from Human CHEK1 (AA 254-264). This peptide sequence corresponds to amino acid residues: ITIPDIKKDRW.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Alternative Name
Checkpoint Kinase 1; Cell Cycle Checkpoint Kinase; CHK1 Checkpoint Homolog; EC 2.7.11.1; CHK1; Serine/Threonine-Protein Kinase Chk1; Checkpoint, S. Pombe, Homolog Of, 1
Entrez Gene ID
UniProt ID
Cat PEP-011513CQ
Conjugates
Size
Price $
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