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Mouse DBH Peptide (TYWCYITEL) (PEP-189359CQ)

This product is synthetic peptide that is derived from Mouse DBH (AA 233-241). This peptide sequence corresponds to amino acid residues: TYWCYITEL.
Specificity
Mouse
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.
Alternative Name
dopamine beta hydroxylase
Entrez Gene ID
UniProt ID
Cat PEP-189359CQ
Conjugates
Size
Price $
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