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Human DDHD1 Peptide (LYSDATTSKI) (PEP-144901CQ)

This product is synthetic peptide that is derived from Human DDHD1 (AA 112-121). This peptide sequence corresponds to amino acid residues: LYSDATTSKI.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name
DDHD Domain Containing 1; Phosphatidic Acid-Preferring Phospholipase A1 Homolog; Spastic Paraplegia 28 (Autosomal Recessive); PA-PLA1; Phosphatidic Acid-Preferring Phospholipase A1-Like Protein; Phosphatidic Acid-Preferring Phospholipase A1; DDHD Domain-Containing Protein 1;
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat PEP-144901CQ
Conjugates
Size
Price $
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Second antibody and isotype control