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Human ITPR2 Peptide (SPFSDNSTSL) (PEP-032911CQ)

This product is synthetic peptide that is derived from Human ITPR2 (AA 1493-1502). This peptide sequence corresponds to amino acid residues: SPFSDNSTSL.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production.
Alternative Name
Inositol 1,4,5-Trisphosphate Receptor Type 2; ANHD; CFAP48; INSP3R2; IP3R2
Entrez Gene ID
UniProt ID
Cat PEP-032911CQ
Conjugates
Size
Price $
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