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Human papillomavirus type 16 L1 Peptide (DTYRF) (PEP-171968CQ)

This product is synthetic peptide that is derived from Human papillomavirus type 16 L1 (AA 442-446). This peptide sequence corresponds to amino acid residues: DTYRF.
Specificity
HPV16
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
L1 forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Alternative Name
HpV16gp8
Entrez Gene ID
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Cat PEP-171968CQ
Conjugates
Size
Price $
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Second antibody and isotype control