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Human MADD Peptide (SVIGVSPAV) (PEP-034663CQ)

This product is synthetic peptide that is derived from Human MADD (AA 1178-1186). This peptide sequence corresponds to amino acid residues: SVIGVSPAV.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
Alternative Name
MAP Kinase Activating Death Domain; Differentially Expressed In Normal And Neoplastic Cells; Insulinoma Glucagonoma Clone 20; Rab3 GDP/GTP Exchange Factor; DENN; IG20
Entrez Gene ID
UniProt ID
Cat PEP-034663CQ
Conjugates
Size
Price $
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