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Human MAPKBP1 Peptide (RLLDKWVEL) (PEP-097399CQ)

This product is synthetic peptide that is derived from Human MAPKBP1 (AA 92-100). This peptide sequence corresponds to amino acid residues: RLLDKWVEL.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
Alternative Name
Mitogen-Activated Protein Kinase Binding Protein 1; JNK-Binding Protein 1; JNKBP-1; JNKBP1; Mitogen Activated Protein Kinase Binding Protein 1; Mitogen-Activated Protein Kinase-Binding Protein 1; KIAA0596; NPHP20;
Entrez Gene ID
UniProt ID
Cat PEP-097399CQ
Conjugates
Size
Price $
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