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Human SECISBP2 Peptide (AEEFPNLAVA) (PEP-050114CQ)

This product is synthetic peptide that is derived from Human SECISBP2 (AA 406-415). This peptide sequence corresponds to amino acid residues: AEEFPNLAVA.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.
Alternative Name
SECIS Binding Protein 2; Sec Insertion Sequence-Binding Protein 2; SBP2; Selenocysteine Insertion Sequence-Binding Protein 2; SECIS-Binding Protein 2
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat PEP-050114CQ
Conjugates
Size
Price $
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Second antibody and isotype control