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Human SETD2 Peptide (RLNDSPTL) (PEP-050603CQ)

This product is synthetic peptide that is derived from Human SETD2 (AA 620-627). This peptide sequence corresponds to amino acid residues: RLNDSPTL.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Alternative Name
SET Domain Containing 2; Protein-Lysine N-Methyltransferase SETD2; Huntingtin-Interacting Protein B; Lysine N-Methyltransferase 3A; Huntingtin Yeast Partner B; EC 2.1.1.43; P231HBP; HIP-1; HIF-1; KMT3A; HYPB; SET2
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat PEP-050603CQ
Conjugates
Size
Price $
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Second antibody and isotype control