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CNTN4

CNTN4 (Contactin 4) is a Protein Coding gene. Diseases associated with CNTN4 include Spinocerebellar Ataxia Type 16 and Chromosome 3Pter-P25 Deletion Syndrome. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. An important paralog of this gene is CNTN3.
Full Name
Contactin 4
Function
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Biological Process
Axonal fasciculation Source: UniProtKB
Axon guidance Source: GO_Central
Axonogenesis Source: UniProtKB
Brain development Source: UniProtKB
Dendrite self-avoidance Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: GO_Central
Negative regulation of neuron differentiation Source: UniProtKB
Nervous system development Source: UniProtKB
Neuron cell-cell adhesion Source: UniProtKB
Neuron projection development Source: UniProtKB
Regulation of synaptic plasticity Source: UniProtKB
Cellular Location
Secreted; Cell membrane
Involvement in disease
A chromosomal aberration involving CNTN4 has been found in a boy with characteristic physical features of 3p deletion syndrome (3PDS). Translocation t(3;10)(p26;q26). 3PDS is a rare contiguous gene disorder involving the loss of the telomeric portion of the short arm of chromosome 3 and characterized by developmental delay, growth retardation, and dysmorphic features.

Anti-CNTN4 antibodies

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Target: CNTN4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1067
Application*: WB
Target: CNTN4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: BA0362
Application*: P, WB
Target: CNTN4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG756
Application*: IF: 1:100~1:500 ELISA: 1:20000
Target: CNTN4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C3013
Application*: E, IC, IF
Target: CNTN4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C2961
Application*: E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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