CYP4X1

CYP4X1 (Cytochrome P450 Family 4 Subfamily X Member 1) is a Protein Coding gene. Among its related pathways are superpathway of tryptophan utilization and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP4Z1.

Cytochrome P450 Family 4 Subfamily X Member 1

A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).

Endoplasmic reticulum membrane; Microsome membrane

Helical: 14-34