IGSF11

IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).

Full Name

Immunoglobulin Superfamily Member 11

Function

Functions as a cell adhesion molecule through homophilic interaction.

Biological Process

Homophilic cell adhesion via plasma membrane adhesion molecules Source: UniProtKB
Maintenance of protein location Source: Ensembl
Positive regulation of long-term synaptic potentiation Source: Ensembl
Positive regulation of mini excitatory postsynaptic potential Source: Ensembl
Regulation of growth Source: UniProtKB-KW

Cellular Location

Cell membrane

Topology

Extracellular: 23-241
Helical: 242-262
Cytoplasmic: 263-431

PTM

N-glycosylated.

Anti-IGSF11 antibodies

Mouse Anti-IGSF11 Recombinant Antibody (CBYY-I1903) (CBMAB-I3073-YY)

Datasheet

SDS

Target: IGSF11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I1903

Application*: WB, IH

Mouse Anti-IGSF11 Recombinant Antibody (CBYY-I1955) (CBMAB-I3125-YY)

Datasheet

SDS

Target: IGSF11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I1955

Application*: WB

Mouse Anti-IGSF11 Recombinant Antibody (CBYY-I2014) (CBMAB-I3184-YY)

Datasheet

SDS

Target: IGSF11

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYY-I2014

Application*: WB

Mouse Anti-IGSF11 Recombinant Antibody (CBYY-I2037) (CBMAB-I3207-YY)

Datasheet

SDS

Target: IGSF11

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-I2037

Application*: WB, IH

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)