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UBXN6

May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622).

Anti-UBXN6 antibodies

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Mouse Anti-UBXN6 Recombinant Antibody (9E105) (CBMAB-C4426-CN)

Target: UBXN6
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: 9E105
Application*: IF, IP, WB

Mouse Anti-UBXN6 Recombinant Antibody (9E104) (CBMAB-C4425-CN)

Target: UBXN6
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Human
Clone: 9E104
Application*: IF, IP, WB

Mouse Anti-UBXN6 Recombinant Antibody (5C3-1) (CBMAB-C4424-CN)

Target: UBXN6
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: 5C3-1
Application*: WB, IP, IF

Mouse Anti-UBXN6 Recombinant Antibody (2F8-24) (CBMAB-C4423-CN)

Target: UBXN6
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human, Mouse
Clone: 2F8-24
Application*: WB, IP, IF
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)