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Human TG Peptide (EKVPESKVIFDANAPVAVRSKVPDSEF) (PEP-101561CQ)

This product is synthetic peptide that is derived from Human TG (AA 1571-1597). This peptide sequence corresponds to amino acid residues: EKVPESKVIFDANAPVAVRSKVPDSEF.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Alternative Name
Thyroglobulin; AITD3; TGN; Tg;
Entrez Gene ID
UniProt ID
Cat PEP-101561CQ
Conjugates
Size
Price $
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