ETFDH

This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

Full Name

Electron Transfer Flavoprotein Dehydrogenase

Research Area

Accepts electrons from ETF and reduces ubiquinone.

Biological Process

Electron transport chain Source: UniProtKB
Fatty acid beta-oxidation using acyl-CoA dehydrogenase Source: BHF-UCL
Respiratory electron transport chain Source: Reactome
Response to oxidative stress Source: UniProtKB

Cellular Location

Mitochondrion inner membrane

Involvement in disease

Glutaric aciduria 2C (GA2C):
An autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.

Anti-ETFDH antibodies

Mouse Anti-ETFDH Recombinant Antibody (CBFYE-1329) (CBMAB-E1937-FY)

Datasheet

SDS

Target: ETFDH

Host: Mouse

Antibody Isotype: IgG1

Specificity: Mouse, Rat, Cattle, Human

Clone: CBFYE-1329

Application*: WB, P, F, IF, E

Mouse Anti-ETFDH Recombinant Antibody (CBFYE-1330) (CBMAB-E1938-FY)

Datasheet

SDS

Target: ETFDH

Host: Mouse

Specificity: Human

Clone: CBFYE-1330

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)