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IGL

Immunoglobulins recognize foreign antigens and initiate immune responses such as the complement system and phagocytosis. Each immunoglobulin molecule is constituted by two identical heavy chains and two identical light chains. Kappa and lambda are two classes of light chains. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species.
Full Name
Immunoglobulin Lambda Locus

Anti-IGL antibodies

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Rat Anti-Igl Recombinant Antibody (CBYJL-2426) (CBMAB-L2760-YJ)

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Target: IGL
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJL-2426
Application*: E, C, WB
Datasheet SDS

Mouse Anti-IGL Recombinant Antibody (HIglambda) (CBMAB-L0442-YJ)

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Target: IGL
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: HIglambda
Application*: F, IF
Datasheet SDS

Mouse Anti-IGL Recombinant Antibody (CBYJL-1030) (CBMAB-L0441-YJ)

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Target: IGL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1030
Application*: E, F, IH
Datasheet SDS

Goat Anti-IGL Recombinant Antibody (CBYJL-1029) (CBMAB-L0440-YJ)

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Target: IGL
Host: Goat
Antibody Isotype: Ig
Specificity: Human
Clone: CBYJL-1029
Application*: E, F, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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