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LSM1

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM
Full Name
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165).
Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
Biological Process
Deadenylation-dependent decapping of nuclear-transcribed mRNAManual Assertion Based On ExperimentIBA:GO_Central
Histone mRNA catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
mRNA processingManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of neuron differentiationIEA:Ensembl
RNA metabolic processManual Assertion Based On ExperimentIBA:GO_Central
RNA splicingManual Assertion Based On ExperimentTAS:ProtInc
RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB
Stem cell population maintenanceIEA:Ensembl
Cellular Location
Cytoplasm
Cytoplasm, P-body
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Anti-LSM1 antibodies

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Mouse Anti-LSM1 Recombinant Antibody (4F7) (CBMAB-A5084-LY)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F7
Application*: WB, E
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (CBYCL-503) (CBMAB-L0404-YC)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-503
Application*: E, WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (CBYJL-2062) (CBMAB-L2195-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYJL-2062
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (9D7) (CBMAB-L2194-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 9D7
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (5E6) (CBMAB-L2193-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E6
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (CBYJL-2061) (CBMAB-L2192-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog
Clone: CBYJL-2061
Application*: F, IF, IH, WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (CBYJL-2060) (CBMAB-L2190-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-2060
Application*: E, WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (1F5) (CBMAB-L2189-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F5
Application*: WB
Datasheet SDS

Mouse Anti-LSM1 Recombinant Antibody (CBYJL-2600) (CBMAB-L2188-YJ)

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Target: LSM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-2600
Application*: F, IF, WB
Datasheet SDS

Rabbit Anti-LSM1 Recombinant Antibody (CBYJL-2059) (CBMAB-L2187-YJ)

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Target: LSM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2059
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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