PPAT

PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway.

Full Name

Phosphoribosyl Pyrophosphate Amidotransferase

Function

Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.

Biological Process

de novo' AMP biosynthetic processIEA:Ensembl
'de novo' IMP biosynthetic processIEA:UniProtKB-UniPathway
'de novo' XMP biosynthetic processIEA:Ensembl
Glutamine metabolic processIEA:UniProtKB-KW
GMP biosynthetic processIEA:Ensembl
Purine nucleobase biosynthetic processIEA:InterPro
Purine nucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytosol

Anti-PPAT antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-PPAT Recombinant Antibody (3C6) (CBMAB-P2499-YC)

Datasheet

SDS

Target: PPAT

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3C6

Application*: P, WB

Mouse Anti-PPAT Recombinant Antibody (V2-358174) (CBMAB-P2498-YC)

Datasheet

SDS

Target: PPAT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-358174

Application*: F, WB

Mouse Anti-PPAT Recombinant Antibody (1B8) (CBMAB-P2497-YC)

Datasheet

SDS

Target: PPAT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Dog, Rat, Monkey, Mouse

Clone: 1B8

Application*: WB, IH

Mouse Anti-PPAT Recombinant Antibody (1B11) (CBMAB-P2496-YC)

Datasheet

SDS

Target: PPAT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1B11

Application*: WB, IH

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)