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Mouse Anti-PPAT Recombinant Antibody (1B8) (CBMAB-P2497-YC)

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Datasheet
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Basic Information

Host Animal
Mouse
Clone
1B8
Application
WB, IHC
Specificity
Human, Dog, Rat, Monkey, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Phosphoribosyl Pyrophosphate Amidotransferase
Introduction
PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway.
Entrez Gene ID
Human5471
Mouse231327
Rat117544
Dog611407
Monkey694868
UniProt ID
HumanQ06203
MouseQ8CIH9
RatP35433
DogE2RF42
MonkeyF7GPV9
Alternative Names
GPAT; ATASE; PRAT
Function
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Biological Process
de novo' AMP biosynthetic processIEA:Ensembl
'de novo' IMP biosynthetic processIEA:UniProtKB-UniPathway
'de novo' XMP biosynthetic processIEA:Ensembl
Glutamine metabolic processIEA:UniProtKB-KW
GMP biosynthetic processIEA:Ensembl
Purine nucleobase biosynthetic processIEA:InterPro
Purine nucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytosol
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-PPAT Recombinant Antibody (3C6) (CAT#: CBMAB-P2499-YC)

Mouse Anti-PPAT Recombinant Antibody (1B11) (CAT#: CBMAB-P2496-YC)

Mouse Anti-PPAT Recombinant Antibody (V2-358174) (CAT#: CBMAB-P2498-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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