Developmental Biology Research
The ontogenetic trajectory from a unicellular zygote to a functionally integrated, multicellular organism represents a biological process of immense complexity. Developmental biology endeavors to elucidate the mechanisms governing this remarkable transformation. It seeks to answer the fundamental question: how do cells with identical genetic information differentiate to form the vast array of tissues and organs that constitute a living being? This field explores the precise orchestration of gene expression, cell signaling, and physical morphogenesis that guides the formation of a structured body plan from an unstructured zygote.
Pivotal to these developmental programs are a set of highly conserved signaling pathways, including Wnt, Notch, Hedgehog, and TGF-β, which are deployed iteratively as master regulators. Their activity governs a suite of fundamental cellular behaviors: fate specification, proliferation, coordinated migration, and programmed cell death. It is through these intricate molecular cascades, perhaps, that signals first establish the global body axes (for instance, the anterior-posterior axis), and subsequently direct the fine-scale sculpting of tissues. Therefore, elucidating these mechanisms extends far beyond fundamental biology; such knowledge provides a critical framework for understanding the etiology of congenital anomalies, and the aberrant signaling implicated in neoplasia, and informs nascent strategies in regenerative medicine and tissue engineering.
Accurate identification and localization of key regulatory proteins, transcription factors, and signaling molecules are crucial for understanding developing tissues. Creative Biolabs offers researchers superior-quality, meticulously validated antibodies optimized for applications such as immunohistochemistry and western blotting. Our extensive catalog of developmental biology antibodies provides the precision needed to track the expression of critical transcription factors or map signaling gradients, helping researchers unlock discoveries.
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Target: CTNND1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXC-2757
Application*: WB
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Target: COL1A2
Host: Mouse
Antibody Isotype: IgG1, λ
Specificity: Human, Mouse, Rat
Clone: CF108
Application*: WB, IP, IF, E, P
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Target: COL1A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-2045
Application*: P, IF
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Target: COL1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2041
Application*: E
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Target: FOLR1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1219
Application*: WB: 1:500~1:1000 ELISA: 1:1000
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Target: FOLR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF173
Application*: ELISA, WB, IHC
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Target: H2BC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: RM235
Application*: ELISA, ICC, WB
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Target: TdT
Host: Mouse
Specificity: Human
Clone: IHC671
Application*: P, E, IH
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Target: POLR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey, Hamster, Cattle
Clone: D8L4Y
Application*: WB, CI, CI-seq
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Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4748
Application*: F, IF, P, WB
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Target: PRKX
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H7
Application*: E, IP, WB
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Target: PODXL
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Rat, Rabbit
Clone: 2A4
Application*: F, P
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Target: KIRREL1
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: G-8
Application*: WB, IP, IF, E
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Target: FUT7
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3241
Application*: E
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Target: FUT4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6B11B4
Application*: E, WB, P, IF, F
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Target: OIT3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-619
Application*: WB, IC, P, C, E
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Target: LGALS12
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-256
Application*: WB, IC, P, C, E
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Target: GTF2A1L
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2092
Application*: E, WB
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Target: RBP4
Host: Mouse
Specificity: Human
Clone: 06
Application*: E
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Target: GH1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1100
Application*: E, P
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For Research Use Only. Not For Clinical Use.