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STXBP4

Full Name
syntaxin binding protein 4
Function
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).
Biological Process
Biological Process cellular response to DNA damage stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process insulin receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell cycle G1/S phase transitionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of keratinocyte proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein stabilizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein targetingIEA:Ensembl
Biological Process regulation of glucose transmembrane transportIEA:Ensembl
Biological Process regulation of insulin secretion involved in cellular response to glucose stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
PTM
Phosphorylated on Ser-99 by PKB/AKT2 after insulin treatment. Phosphorylation on Ser-99 abolishes the interaction with STX4A (By similarity).
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Anti-STXBP4 antibodies

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Mouse Anti-STXBP4 Recombinant Antibody (2B12) (CBMAB-A8754-LY)

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Target: STXBP4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2B12
Application*: WB, E
Datasheet SDS

Rabbit Anti-STXBP4 Recombinant Antibody (CBXS-6166) (CBMAB-S6381-CQ)

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Target: STXBP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXS-6166
Application*: WB
Datasheet SDS

Rabbit Anti-STXBP4 Recombinant Antibody (CBXS-3416) (CBMAB-S6150-CQ)

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Target: STXBP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXS-3416
Application*: E, WB
Datasheet SDS

Mouse Anti-STXBP4 Recombinant Antibody (CBXS-2837) (CBMAB-S5587-CQ)

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Target: STXBP4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-2837
Application*: E, WB
Datasheet SDS

Rabbit Anti-STXBP4 Recombinant Antibody (CBXS-1202) (CBMAB-S4066-CQ)

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Target: STXBP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1202
Application*: WB, P, F
Datasheet SDS

Rabbit Anti-STXBP4 Recombinant Antibody (CBXS-0835) (CBMAB-S3759-CQ)

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Target: STXBP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0835
Application*: E, WB
Datasheet SDS

Rabbit Anti-STXBP4 Recombinant Antibody (CBXS-5999) (CBMAB-S0845-CQ)

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Target: STXBP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXS-5999
Application*: WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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