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TSNAX

TSNAX is a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. TSNAX contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs.

Full Name

Translin Associated Factor X

Function

Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process siRNA processing Source:ComplexPortal1 Publication
Biological Process spermatogenesis Source:UniProtKB-KW

Cellular Location

Cytoplasm, perinuclear region
Golgi apparatus
Nucleus
Accumulate in the Golgi complex of mid-late pachytene spermatocytes (By similarity).
Expressed in the cytoplasm in the presence of TSN

PTM

Sumoylated with SUMO1.

Anti-TSNAX antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-TSNAX Recombinant Antibody (CBYJT-5060) (CBMAB-T4637-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat, Mouse

Clone: CBYJT-5060

Application*: WB, IP, IF, E

Mouse Anti-TSNAX Recombinant Antibody (CBYJT-5059) (CBMAB-T4636-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat, Mouse

Clone: CBYJT-5059

Application*: WB, IP, IF, E

Mouse Anti-TSNAX Recombinant Antibody (CBYJT-5057) (CBMAB-T4634-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgM, κ

Specificity: Human

Clone: CBYJT-5057

Application*: E, WB

Mouse Anti-TSNAX Recombinant Antibody (CBYJT-5056) (CBMAB-T4633-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-5056

Application*: WB

Mouse Anti-TSNAX Recombinant Antibody (CBYJT-5055) (CBMAB-T4632-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgM, κ

Specificity: Human

Clone: CBYJT-5055

Application*: E, WB

Mouse Anti-TSNAX Recombinant Antibody (3179C2a) (CBMAB-T4631-YJ)

SDS

Target: TSNAX

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3179C2a

Application*: DB, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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