CALCB

CALCB (Calcitonin Related Polypeptide Beta) is a Protein Coding gene. Diseases associated with CALCB include Thyroid Carcinoma, Familial Medullary. Among its related pathways are Peptide ligand-binding receptors and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include hormone activity and neuropeptide hormone activity. An important paralog of this gene is CALCA.

Calcitonin Related Polypeptide Beta

CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cellular calcium ion homeostasis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Negative regulation of inflammatory response to antigenic stimulus Source: Reactome
Regulation of cytosolic calcium ion concentration Source: GO_Central
Signal transduction Source: ProtInc

Secreted