COA6

COA6 (Cytochrome C Oxidase Assembly Factor 6) is a Protein Coding gene.

Cytochrome C Oxidase Assembly Factor 6

Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.

Plasma membrane ATP synthesis coupled electron transport Source: UniProtKB
Respiratory chain complex IV assembly Source: UniProtKB

Mitochondrion intermembrane space