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Mouse Anti-COA6 Recombinant Antibody (4A6) (CBMAB-C6605-LY)

This product is antibody recognizes COA6. The antibody 4A6 immunoassay techniques such as: ELISA, WB.
See all COA6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4A6
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
C1orf31 (NP_001013003.1, aa1-125) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cytochrome C Oxidase Assembly Factor 6
Introduction
COA6 (Cytochrome C Oxidase Assembly Factor 6) is a Protein Coding gene. Diseases associated with COA6 include Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency 4 and Fatal Infantile Cytochrome C Oxidase Deficiency. Among its related pathways are Metabolism of proteins and Mitochondrial protein import.
Gene Ontology (GO) annotations related to this gene include cytochrome-c oxidase activity.
Entrez Gene ID
388753
UniProt ID
Q5JTJ3
Alternative Names
Cytochrome C Oxidase Assembly Factor 6; C1orf31; Cytochrome C Oxidase Assembly Factor 6 Homolog (S. Cerevisiae); Cytochrome C Oxidase Assembly Factor 6 Homolog; Chromosome 1 Open Reading Frame 31; CEMCOX4;
Function
Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
Biological Process
Plasma membrane ATP synthesis coupled electron transport Source: UniProtKB
Respiratory chain complex IV assembly Source: UniProtKB
Cellular Location
Mitochondrion intermembrane space
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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