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CTXA

Member of the alpha-actinin/spectrin superfamily, dimerizes with cortexillin II; involved in cytokinesis and development and associates with the actin cytoskeleton.
Full Name
Actin binding protein
Function
Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1.
Biological Process
Actin filament bundle assembly Source: dictyBase
Actin filament network formation Source: dictyBase
Actomyosin contractile ring contraction Source: dictyBase
Aggregation involved in sorocarp development Source: dictyBase
Bleb assembly Source: dictyBase
Cellular protein localization Source: dictyBase
Chemotaxis to cAMP Source: dictyBase
Cleavage furrow formation Source: dictyBase
Cortical actin cytoskeleton organization Source: dictyBase
Detection of mechanical stimulus Source: dictyBase
Epithelial cell morphogenesis Source: dictyBase
Establishment of protein localization Source: dictyBase
Mitotic cytokinesis Source: dictyBase
Positive regulation of cytoskeleton organization Source: dictyBase
Positive regulation of gene expression Source: dictyBase
Positive regulation of protein phosphorylation Source: dictyBase
Protein localization to cleavage furrow Source: dictyBase
Regulation of GTPase activity Source: dictyBase
Regulation of myosin II filament assembly Source: dictyBase
Response to bacterium Source: dictyBase
Sexual reproduction Source: dictyBase
Sorocarp stalk morphogenesis Source: dictyBase
Cellular Location
Cytoskeleton

Anti-CTXA antibodies

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Target: CTXA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: D. discoideum, Dictyostelium
Clone: 241-438-1
Application*: B, IH, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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