GNAT2

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.

G protein subunit alpha transducin 2

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Detection of chemical stimulus involved in sensory perception of bitter taste Source: GO_Central
Detection of light stimulus involved in visual perception Source: UniProtKB
G protein-coupled receptor signaling pathway Source: UniProtKB
Phototransduction Source: UniProtKB
Visual perception Source: UniProtKB

Photoreceptor outer segmen; Photoreceptor inner segment. Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.

Achromatopsia 4 (ACHM4):
An ocular stationary disorder due to the absence of functioning cone photoreceptors in the retina. It is characterized by total colorblindness, low visual acuity, photophobia and nystagmus.