HAPLN1

HAPLN1 (Hyaluronan And Proteoglycan Link Protein 1) is a Protein Coding gene. Diseases associated with HAPLN1 include Juvenile Rheumatoid Arthritis and Cerebral Creatine Deficiency Syndrome 3. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent and hyaluronic acid binding. An important paralog of this gene is HAPLN3.

Hyaluronan And Proteoglycan Link Protein 1

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Cell adhesion Source: InterPro
Central nervous system development Source: GO_Central
Skeletal system development Source: GO_Central

Extracellular matrix