IGSF3

The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD).
Full Name
immunoglobulin superfamily, member 3
Function
Lacrimal gland development Source: UniProtKB
Cellular Location
Membrane
Involvement in disease
Lacrimal duct defect (LCDD):
A condition resulting in the imbalance between tear production and tear drainage. Infants typically manifest persistent epiphora and/or recurrent infections of the lacrimal pathway, such as conjunctivitis. LCDD is caused by failure of the nasolacrimal duct to open into the inferior meatus.
Topology
Extracellular: 20-1124
Helical: 1125-1145
Cytoplasmic: 1146-1194
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Anti-IGSF3 antibodies

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Human Recombinant IGSF3 protein, His Tag (V2LY-0526-LY4695)

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Target: IGSF3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-1124
Tag: His Tag
Datasheet SDS

Mouse Anti-IGSF3 Recombinant Antibody (503621) (CBMAB-I1377-YY)

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Target: IGSF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 503621
Application*: WB, F, MC
Datasheet SDS

Mouse Anti-IGSF3 Recombinant Antibody (CBYY-I0115) (CBMAB-I0330-YY)

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Target: IGSF3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I0115
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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