KLK11

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK11 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.

Full Name

Kallikrein Related Peptidase 11

Function

Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.

Biological Process

Isoform 1
Secreted
Isoform 2
Golgi apparatus

PTM

About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.

Anti-KLK11 antibodies

Mouse Anti-KLK11 Recombinant Antibody (CBYJT-1411) (CBMAB-T0434-YJ)

Datasheet

SDS

Target: KLK11

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-1411

Application*: WB, IC, P, C, E

Rabbit Anti-KLK11 Recombinant Antibody (CBFYH-2608) (CBMAB-H3634-FY)

Datasheet

SDS

Target: KLK11

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2608

Application*: E, WB

Mouse Anti-KLK11 Recombinant Antibody (6A7B2C7) (CBMAB-K1213-LY)

Datasheet

SDS

Target: KLK11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6A7B2C7

Application*: E

Rat Anti-KLK11 Recombinant Antibody (371604) (CBMAB-K1211-LY)

Datasheet

SDS

Target: KLK11

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: 371604

Application*: N

Mouse Anti-KLK11 Recombinant Antibody (14L658) (CBMAB-K1210-LY)

Datasheet

SDS

Target: KLK11

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 14L658

Application*: IH, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)