NTS

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq]

neurotensin

Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Antimicrobial humoral immune response mediated by antimicrobial peptideIDA:UniProtKB
Killing of cells of another organismIDA:UniProtKB
Negative regulation of gene expressionManual Assertion Based On ExperimentIDA:ARUK-UCL
Neuropeptide signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of gene expressionManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of NF-kappaB transcription factor activityManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of protein kinase B signalingManual Assertion Based On ExperimentIDA:ARUK-UCL
Signal transduction1 PublicationNAS:ProtInc

Secreted
Cytoplasmic vesicle, secretory vesicle
Packaged within secretory vesicles.