S. cerevisiae RAD53

Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1.

serine/threonine/tyrosine protein kinase RAD53

Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1.

Biological Process deoxyribonucleoside triphosphate biosynthetic processManual Assertion Based On ExperimentIMP:SGD
Biological Process DNA damage checkpoint signalingManual Assertion Based On ExperimentIGI:SGD
Biological Process DNA repairManual Assertion Based On ExperimentIMP:SGD
Biological Process DNA replication initiationManual Assertion Based On ExperimentIMP:SGD
Biological Process mitotic DNA damage checkpoint signalingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of DNA damage checkpoint1 PublicationIC:ComplexPortal
Biological Process negative regulation of phosphorylationManual Assertion Based On ExperimentIMP:SGD
Biological Process positive regulation of cellular respirationManual Assertion Based On ExperimentIMP:SGD
Biological Process protein localizationManual Assertion Based On ExperimentIMP:SGD
Biological Process regulation of DNA repair1 PublicationIC:ComplexPortal

Nucleus

Autophosphorylated.