CDKN2C

CDKN2C (Cyclin Dependent Kinase Inhibitor 2C) is a Protein Coding gene. Diseases associated with CDKN2C include Oligodendroglioma and Choriocarcinoma Of The Testis. Among its related pathways are Cellular Senescence (REACTOME) and Endometrial cancer. Gene Ontology (GO) annotations related to this gene include protein kinase binding and cyclin-dependent protein serine/threonine kinase inhibitor activity. An important paralog of this gene is CDKN2D.

Cyclin Dependent Kinase Inhibitor 2C

Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

Cell cycle arrest Source: BHF-UCL
G1/S transition of mitotic cell cycle Source: BHF-UCL
Negative regulation of cell growth Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Negative regulation of G1/S transition of mitotic cell cycle Source: Reactome
Negative regulation of phosphorylation Source: BHF-UCL
Oligodendrocyte differentiation Source: Ensembl
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: BHF-UCL

Cytosol; Nucleus; Cytoplasm