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Mouse Anti-CDKN2C Recombinant Antibody (CBYY-I1699) (CBMAB-I2869-YY)

This product is Mouse antibody that recognizes CDKN2C. The antibody CBYY-I1699 can be used for immunoassay techniques such as: WB, IP
See all CDKN2C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-I1699
Antibody Isotype
IgG2a
Application
WB, IP

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cyclin Dependent Kinase Inhibitor 2C
Introduction
CDKN2C (Cyclin Dependent Kinase Inhibitor 2C) is a Protein Coding gene. Diseases associated with CDKN2C include Oligodendroglioma and Choriocarcinoma Of The Testis. Among its related pathways are Cellular Senescence (REACTOME) and Endometrial cancer.
Entrez Gene ID
UniProt ID
Alternative Names
Cyclin Dependent Kinase Inhibitor 2C; Cyclin-Dependent Kinase Inhibitor 2C (P18, Inhibits CDK4); P18-INK4C; P18-INK6; Cyclin-Dependent Kinase 6 Inhibitor P18; Cyclin-Dependent Kinase 4 Inhibitor C; Cyclin-Dependent Kinase 6 Inhibitor;
Function
Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Biological Process
Cell cycle arrest Source: BHF-UCL
G1/S transition of mitotic cell cycle Source: BHF-UCL
Negative regulation of cell growth Source: BHF-UCL
Negative regulation of cell population proliferation Source: BHF-UCL
Negative regulation of G1/S transition of mitotic cell cycle Source: Reactome
Negative regulation of phosphorylation Source: BHF-UCL
Oligodendrocyte differentiation Source: Ensembl
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: BHF-UCL
Cellular Location
Cytosol; Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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