CYTH3

CYTH3 (Cytohesin 3) is a Protein Coding gene. Among its related pathways are Angiopoietin Like Protein 8 Regulatory Pathway and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol-3,4,5-trisphosphate binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is CYTH1.

Full Name

Cytohesin 3

Function

Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity).

Biological Process

Establishment of epithelial cell polarity Source: UniProtKB
Golgi vesicle transport Source: UniProtKB
Positive regulation of cell adhesion Source: Ensembl
Regulation of ARF protein signal transduction Source: InterPro

Cellular Location

Cell membrane; Cytosol; Adherens junction; Tight junction. Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate.

Anti-CYTH3 antibodies

Mouse Anti-CYTH3 Recombinant Antibody (CBCNC-107) (CBMAB-C1002-CN)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBCNC-107

Application*: E, ICC, WB

Mouse Anti-CYTH3 Recombinant Antibody (6D3-1A9) (CBMAB-A7115-LY)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 6D3-1A9

Application*: WB, E

Mouse Anti-CYTH3 Recombinant Antibody (CBYY-C2405) (CBMAB-C3843-YY)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBYY-C2405

Application*: E, IF, WB

Mouse Anti-CYTH3 Recombinant Antibody (CBXC-0639) (CBMAB-C3718-CQ)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXC-0639

Application*: WB, SE, E, IF

Mouse Anti-CYTH3 Recombinant Antibody (S1) (CBMAB-C11464-LY)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: S1

Application*: E, WB

Mouse Anti-CYTH3 Recombinant Antibody (CBWJC-3583) (CBMAB-C4821WJ)

Datasheet

SDS

Target: CYTH3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: CBWJC-3583

Application*: E, IC, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)