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Mouse Anti-CYTH3 Recombinant Antibody (S1) (CBMAB-C11464-LY)

The product is antibody recognizes CYTH3. The antibody S1 immunoassay techniques such as: ELISA, WB.
See all CYTH3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
S1
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
CYTH3 (AAH08191.1, 1 a.a. ~ 179 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MNRGINEGGD LPEELLRNLY ESIKNEPFKI PEDDGNDLTH TFFNPDREGW LLKLGGRVKT WKRRWFILTD NCLYYFEYTT DKEPRGIIPL ENLSIREVED PRKPNCFELY NPSHKGQVIK ACKTEADGRV VEGNHVVYRI SAPSPEEKEE WMKSIKASIS RDPFYDMLAT RKRRIANKK
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cytohesin 3
Introduction
CYTH3 (Cytohesin 3) is a Protein Coding gene. Among its related pathways are Angiopoietin Like Protein 8 Regulatory Pathway and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol-3,4,5-trisphosphate binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is CYTH1.
Entrez Gene ID
9265
UniProt ID
O43739
Alternative Names
Cytohesin 3; PH, SEC7 And Coiled-Coil Domain-Containing Protein 3; Pleckstrin Homology, Sec7 And Coiled-Coil Domains 3; General Receptor Of Phosphoinositides 1; ARF Nucleotide-Binding Site Opener 3; PSCD3;
Function
Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity).
Biological Process
Establishment of epithelial cell polarity Source: UniProtKB
Golgi vesicle transport Source: UniProtKB
Positive regulation of cell adhesion Source: Ensembl
Regulation of ARF protein signal transduction Source: InterPro
Cellular Location
Cell membrane; Cytosol; Adherens junction; Tight junction. Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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