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Mouse Anti-CYTH3 Recombinant Antibody (CBYY-C2405) (CBMAB-C3843-YY)

This product is mouse antibody that recognizes CYTH3. The antibody CBYY-C2405 can be used for immunoassay techniques such as: ELISA, IF, WB
See all CYTH3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2405
Antibody Isotype
IgG2b, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa1-180 from PSCD3 (AAH08191) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cytohesin 3
Entrez Gene ID
9265
UniProt ID
O43739
Alternative Names
Erb-B2 Receptor Tyrosine Kinase 2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185erbB2; MLN 19; HER2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog);
Function
Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity).
Biological Process
Establishment of epithelial cell polarity Source: UniProtKB
Golgi vesicle transport Source: UniProtKB
Positive regulation of cell adhesion Source: Ensembl
Regulation of ARF protein signal transduction Source: InterPro
Cellular Location
Cell membrane; Cytosol; Adherens junction; Tight junction. Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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