Antibody products are traditionally divided into two classes based on whether they directly bind to antigens or not. Primary antibodies directly bind to a particular antigen of interest whereas secondary antibodies are those binding to primary antibodies. Primary antibodies could be conjugated to reporter molecules such as fluorescent dyes, horseradish peroxidase (HRP), alkaline phosphatase (ALP), biotin and so on. Conjugated primary antibodies are highly useful because they can be utilized to create a detectable signal via color-generation, fluorescence, or others. Conjugated primary antibody has no risk of cross-reactivity from secondary antibody but lacks signal amplification and flexibility and may result in high background. However, sometimes the primary antibody is not suitable for conjugation. Under these circumstances, the naked primary antibody and conjugated secondary antibody combination is suitable for you.
Creative Biolabs offers thousands of primary antibodies used as a tool for cancer research for our clients' projects.
Cancer cells are cells that divide relentlessly, forming solid tumors or flooding the blood with abnormal cells. Cell division is a normal process used by the body for growth and repair. We have a broad selection of research antibodies to help your projects in the research of autophagy, metastasis, proliferative signaling, metabolism, and any other cancer-related research.
Creative Biolabs provides a range comprehensive of recombinant antibodies using in the research of post-translational modification (PTM).
PTM are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Many cellular activities are controlled by post-translational modifications, the study of which is hampered by the lack of specific reagents due in large part to their ubiquitous and non-immunogenic nature. The most common modifications are the specific cleavage of precursor proteins, formation of disulfide bonds, or covalent addition or removal of low-molecular-weight groups, thus leading to modifications such as acetylation, amidation, biotinylation, cysteinylation, deamidation, farnesylation, formylation, geranylgeranylation, glutathionylation, glycation (nonenzymatic conjugation with carbohydrates), glycosylation (enzymatic conjugation with carbohydrates), hydroxylation, methylation, and so on. PTM play a fundamental role in regulating the folding of proteins, their targeting to specific subcellular compartments, their interaction with ligands or other proteins, and their functional state, such as catalytic activity in the case of enzymes or the signaling function of proteins involved in signal transduction pathways.
Creative Biolabs offers a range comprehensive of high-quality recombinant antibodies for our clients in the research of cardiovascular.
Cardiovascular disease (CVD) is one of the major cause of cell death worldwide. That’s why cardiovascular research is a very important area. CVD is a class of diseases that involve the heart or blood vessels. These diseases include coronary artery diseases such as angina and myocardial infarction. Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, heart arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. An important part of studies on CVD is the identification and characterization of key molecules that can be used on as biomarkers for assessment of patients at the target of therapeutic approaches.
Creative Biolabs provides an extensive collection of cell biology recombinant antibodies, including antibodies for important research areas for apoptosis, cell structure, cell signaling and cell morphology.
Cell biology explains the structure, organization of the organelles, their physiological properties, metabolic processes, signaling pathways, life cycle, and interactions with their environment. Understanding the components and the mechanism of cells is fundamental to all biological sciences. It is also essential for research in bio-medical fields such as cancer, and other diseases.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of epigenetics.
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence Mechanisms of these changes are DNA methylation and histone modification. Our recombinant antibodies can be used to transcription factors, chromatin modifiers and stem cell regulators. To support your research project, you need these antibodies to work in, such as chromatin immunoprecipitation (ChIP), western blot (WB) and immunofluorescence (IF).
Creative Biolabs provides a range comprehensive of recombinant antibodies used in the research of metabolism.
As the environments of most organisms are constantly changing, the reactions of metabolism must be finely regulated to maintain a constant set of conditions within cells, a condition called homeostasis. Metabolic regulation impacts cellular functions and plays a fundamental role in biology. It allows organisms to respond to signals and interact actively with their environments. Our antibodies using in metabolism focuses on the cellular processes, catabolism and anabolism, which support the maintenance of cell functions through the breakdown of molecules for energy and the corresponding use of this energy to construct cell structures such as proteins and nucleic acids.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of developmental biology.
Developmental biology is the study of the process by which animals and plants grow and develop. It is the study of the growth and differentiation of stem cells in the adult organism. Moreover, it also encompasses the biology of regeneration, asexual reproduction and metamorphosis. The main process involved in the embryonic development of the animal are: regional specification, morphogenesis, cell differentiation, growth, and the overall control of timing explored in evolutionary developmental biology. Reginal specification is often referred to as the processes that create the spatial pattern in a ball or sheet of initially similar cells.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of immunology.
Immunology includes the study of molecules and cells of the immune system to disease dynamics in populations and ecosystems. Clinical immunology is the study of diseases which are caused by the disorder of the immune system. These disorders include failure, aberrant action, and malignant growth of the cellular elements of the system. Moreover, Clinical immunology also involves diseases of the other systems, where immune reactions play a part in the pathology and clinal features. The diseases caused by disorders if the immune system falls into two broad categories: immunodeficiency and autoimmunity.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of microbiology.
Microbiology is the study of microorganisms, those being unicellular, multicellular, or acellular. Microbiology encompasses numerous sub-disciplines including virology, parasitology, mycology and bacteriology. We offer recombinant antibodies suitable for ELISA and Western blotting to make it easier for you to carry on your research in microbiology.
Creative Biolabs provides a range comprehensive of recombinant antibodies used in the research of neuroscience.
Neuroscience is the scientific study of the nervous system. It is a multidisciplinary branch of biology, that deals with the anatomy, biochemistry, molecular biology, and physiology of neurons and neural circuits. Prevention and effective treatment of neurological disorders such as Alzheimer’s and Parkinson’s diseases has been a major medical challenge. For that, we developed comprehensive antibodies to support your projects of the nervous system.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of signal transduction.
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response. Proteins responsible for detecting and binding the stimuli are generally referred to as receptors, and in some cases the term sensor is used.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of stem cells.
Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide to produce more stem cells. They are found in multicellular organisms. In mammals, there exists two broad types of stem cells: embryonic stem cells, and adult stem cells. Embryonic stem cells are isolated from the inner cell mass of blastocysts while adult stem cells are found in various tissues. Stem cells differentiate into all the specialized cells such as ectoderm, endoderm and mesoderm - but also maintain the normal turnover of blood, skin, or intestinal tissues.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of cell therapy.
Cell therapy (also called cellular therapy or cytotherapy) is therapy in which cellular material is injected into a patient this generally means intact, living cells. For example, T cells which are capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy. We offer comprehensive antibodies to support your research projects in cell therapy.
Creative Biolabs provides a comprehensive range of recombinant antibodies using in the research of immunotherapy.
Immunotherapy is the treatment of disease by inducing, enhancing, or suppressing an immune response. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies. Recently, immunotherapy has drawn much attention to researchers and clinicians, particularly those who are figuring out ways to treat various forms of cancer.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of ubiquitin proteosome.
Regulating protein stability and turnover is a key task in the cell. Besides lysosomes, ubiquitin-mediated proteasomal degradation comprises the major proteolytic pathway in eukaryotes. Proteins destined for degradation by the proteasome are labeled by a 'tag' through an extensively regulated enzymatic cascade. This ‘tag’ is a small protein termed ubiquitin. The ubiquitylated proteins are subsequently targeted for degradation by the 26S proteasome, the major proteolytic machinery for ubiquitylated proteins in the cell.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of apoptosis and cell viability.
The accurate determination of cell growth and viability is pivotal to monitoring a bioprocess. Apoptosis is a process of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. A viability assay is an assay to determine the ability of organs, cells or tissues to maintain or recover viability. Viability can be distinguished from the all-or-nothing states of life and death by use of a quantifiable index between 0 and 1 (or 0% and 100%). Viability can be classified into assay mechanical activity, motility, contraction, mitotic activity, etc.
Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of glycobiology.
Glycobiology is the study of the structure, biosynthesis, and biology of saccharides (sugar chains or glycans) that are widely distributed in nature. Saccharides are essential components of all living things. Aspects of the various important roles they play in biology are researched in a variety of medical, biochemical and biotechnological fields.