CIZ1

The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene.

Full Name

CIZ1

Function

May regulate the subcellular localization of CIP/WAF1.

Cellular Location

Nucleus

Involvement in disease

Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk.

Anti-CIZ1 antibodies

Mouse Anti-CIZ1 Antibody (V2-4483) (CBMAB-0231-YC)

Datasheet

SDS

Target: CIZ1

Host: Mouse

Antibody Isotype: IgG2c

Specificity: Human

Clone: V2-4483

Application*: IP, M

Mouse Anti-CIZ1 Recombinant Antibody (2186C2a) (CBMAB-C0647-LY)

Datasheet

SDS

Target: CIZ1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2186C2a

Application*: DB, WB

Mouse Anti-CIZ1 Recombinant Antibody (8C96) (CBMAB-C9115-LY)

Datasheet

SDS

Target: CIZ1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 8C96

Application*: WB

Mouse Anti-CIZ1 Recombinant Antibody (CBFYC-1879) (CBMAB-C1944-FY)

Datasheet

SDS

Target: CIZ1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-1879

Application*: DB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)